Wednesday, June 13, 2012

Placebo

What is a placebo

pla·ce·bo/pləˈsēbō/
Noun:
  1. A harmless pill, medicine, or procedure prescribed more for the psychological benefit to the patient than for any physiological effect.
  2. A substance that has no therapeutic effect, used as a control in testing new drugs.



Many vaccine critics find fault with vaccine trials that do not use what they consider to be a true placebo in trials or studies.  Vaccine critics believe placebos are supposed to be completely inert. Since they are concerned with vaccine ingredients, they find it troublesome that vaccine trials still use as a control a substance containing similar ingredients to vaccines. 

So, why do researchers do this?

If you gave a shot of vaccine to one group, and no shot to the other group, it would be obvious to them who got the actual vaccine and who did not. Instead, the people not getting the active vaccine are given a shot with similar ingredients except for the vaccine component. This is consistent with experimental protocol to have as few variables at stake as possible.  You want to control for everything but the one ingredient you are changing, is how it is explained to me. Since vaccine adjuvants are well tested, you don't need to remove them from the study at all when you are testing a new vaccine.